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Memory problems can be caused by several conditions, including the following:

  • Alcoholism and illegal drug use (may interfere with medications and brain chemicals and lead to thiamin deficiency [Wernicke-Korsakoff syndrome])
  • Brain injuries (including concussion, head trauma, and bleeding between the brain and skull) and brain tumors
  • Changes in the brain (e.g., due to the abnormal buildup of proteins or shrinkage of the hippocampus [portion of the brain critical for memory functioning])
  • Creutzfeldt-Jakob disease (rare brain illness that can result in chronic dementia)
  • Dehydration (low levels of fluid in the body)
  • Depression, anxiety, and stress (may trigger memory issues that improve with treatment or psychogenic amnesia [rare])
  • Electroconvulsive therapy
  • Epilepsy and seizures
  • Infections (e.g., HIV/AIDS, tuberculosis, herpes, syphilis)
  • Lack of oxygen to the brain (due to stroke, transient ischemic attack (TIA), heart attack, respiratory problems, and carbon monoxide poisoning)
  • Malnutrition (e.g., lack of thiamin [vitamin B-1] or vitamin B-12)
  • Medications and drug interactions
  • Normal pressure hydrocephalus (NPH; excessive buildup of fluid in the brain can increase pressure and squeeze brain tissue)
  • Overactive or underactive thyroid gland
  • Parkinson's disease
  • Sleep deprivation
  • Wilson's disease (results in too much copper in the body, which can cause brain damage)

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For more information regarding memory loss problems, continue to the following pages:


Raymond Rybicki, MD

This information is for general educational uses only. It may not apply to you and your specific medical needs. This information should not be used in place of a visit, call, consultation with or the advice of your physician or health care professional. Communicate promptly with your physician or other health care professional with any health-related questions or concerns.

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